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Prophylactic antibiotics not necessary before invasive dental procedures – Consumer Health News

THURSDAY, Jan. 20, 2022 (HealthDay News) — According to a study published online Jan. 19 in Open JAMA Network.

Martin H. Thornhill, MBBS, Ph.D., of the University of Sheffield School of Clinical Dentistry in the UK, and colleagues assessed associations between PDI and late prosthetic joint infection (LPJI ) using data from England, where antibiotic prophylaxis has never been recommended to prevent IAPJ. The analysis included 9,427 patients admitted to hospitals in England for LPJI between 25 December 2011 and 31 March 2017.

Researchers found that 25.3% had prosthetic hip joints, 33.6% had prosthetic knee joints, 2.8% had other prosthetic joints, and 38.4% had prosthetic joint types unknown. No significant temporal association was observed between IDP and subsequent LPJI. In fact, there was a lower incidence of IDP observed in the three months preceding the LPJI (incidence rate ratio, 0.89).

“These findings refute recommendations to administer antibiotic prophylaxis to patients with joint prostheses prior to PDI, considering the cost, risk of adverse drug reaction, and potential for promoting antibiotic resistance associated with antibiotic prophylaxis. “, write the authors.

One author disclosed financial ties to the pharmaceutical industry.

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